NME7 Antibody (PACO14773)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO14773
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NME7 Antibody (PACO14773) |
Antibody SKU: | PACO14773 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human NME7 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: PACO14773(NME7 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
Background: | nm23-H7, also known as NME7 (non-metastatic cells 7), is a 376 amino acid, protein that contains one DM10 domain and belongs to the NDK family. Using magnesium as a cofactor, nm23-H7 functions to catalyze the ATP-dependent creation of nucleoside triphosphates, thereby playing an essential role in metabolic pathways throughout the body. The gene encoding nm23-H7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
Synonyms: | NME/NM23 family member 7 |
UniProt Protein Function: | NDK7: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Belongs to the NDK family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Kinase, other; Kinase, nucleoside diphosphate; EC 2.7.4.6; Other group; NDK family Chromosomal Location of Human Ortholog: 1q24 Cellular Component: centrosome Molecular Function:nucleoside diphosphate kinase activity; protein binding |
UniProt Code: | Q9Y5B8 |
NCBI GenInfo Identifier: | 12230353 |
NCBI Gene ID: | 29922 |
NCBI Accession: | Q9Y5B8.1 |
UniProt Secondary Accession: | Q9Y5B8,Q5TGZ4, A8K3T6, A8MY09, B3KSW9, |
UniProt Related Accession: | Q9Y5B8 |
Molecular Weight: | 38,187 Da |
NCBI Full Name: | Nucleoside diphosphate kinase 7 |
NCBI Synonym Full Names: | NME/NM23 family member 7 |
NCBI Official Symbol: | NME7 |
NCBI Official Synonym Symbols: | NDK7; NDK 7; CFAP67; MN23H7; nm23-H7 |
NCBI Protein Information: | nucleoside diphosphate kinase 7 |
UniProt Protein Name: | Nucleoside diphosphate kinase 7 |
UniProt Synonym Protein Names: | nm23-H7 |
Protein Family: | Nucleoside diphosphate kinase |
UniProt Gene Name: | NME7 |
UniProt Entry Name: | NDK7_HUMAN |
Antibodies |
Anti-NME7 Antibody (CAB14882) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |