NKRF Antibody (PACO10863)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO10863
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NKRF Antibody (PACO10863) |
Antibody SKU: | PACO10863 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human NKRF |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | NFKB repressing factor;NKRF;ITBA4;NRF ; |
UniProt Protein Function: | NKRF: Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. |
UniProt Protein Details: | Protein type:Nucleolus; RNA-binding; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: Xq24 Cellular Component: endoplasmic reticulum; nucleolus; nucleus Molecular Function:protein binding; DNA binding Biological Process: transcription, DNA-dependent; negative regulation of transcription, DNA-dependent |
NCBI Summary: | This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
UniProt Code: | O15226 |
NCBI GenInfo Identifier: | 33860178 |
NCBI Gene ID: | 55922 |
NCBI Accession: | O15226.2 |
UniProt Secondary Accession: | O15226,Q4VC41, Q9UJ91, G3V1N1, |
UniProt Related Accession: | O15226 |
Molecular Weight: | 690 |
NCBI Full Name: | NF-kappa-B-repressing factor |
NCBI Synonym Full Names: | NFKB repressing factor |
NCBI Official Symbol: | NKRF |
NCBI Official Synonym Symbols: | NRF; ITBA4 |
NCBI Protein Information: | NF-kappa-B-repressing factor; transcription factor NRF |
UniProt Protein Name: | NF-kappa-B-repressing factor |
UniProt Synonym Protein Names: | Protein ITBA4; Transcription factor NRF |
Protein Family: | NF-kappa-B-repressing factor |
UniProt Gene Name: | NKRF |
UniProt Entry Name: | NKRF_HUMAN |