NEUROG2 Antibody (PACO51146)
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주문- SKU:
- PACO51146
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NEUROG2 Antibody (PACO51146) |
Antibody SKU: | PACO51146 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Human, Rat |
Immunogen: | Recombinant Human Neurogenin-2 protein (194-262AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: U87 whole cell lysate, SH-SY5Y whole cell lysate, Rat lung tissue. All lanes: NEUROG2 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 29 kDa. Observed band size: 29, 60 kDa.. |
Background: | Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). |
Synonyms: | Neurogenin-2 (NGN-2) (Class A basic helix-loop-helix protein 8) (bHLHa8) (Protein atonal homolog 4), NEUROG2, ATOH4 BHLHA8 NGN2 |
UniProt Protein Function: | neurogenin 2: Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').Protein type: Transcription factorChromosomal Location of Human Ortholog: 4q25Biological Process: positive regulation of transcription factor activity |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012] |
UniProt Code: | Q9H2A3 |
NCBI GenInfo Identifier: | 60392832 |
NCBI Gene ID: | 63973 |
NCBI Accession: | Q9H2A3.2 |
UniProt Secondary Accession: | Q9H2A3,Q8N416 |
UniProt Related Accession: | Q9H2A3 |
Molecular Weight: | 28,621 Da |
NCBI Full Name: | Neurogenin-2 |
NCBI Synonym Full Names: | neurogenin 2 |
NCBI Official Symbol: | NEUROG2 |
NCBI Official Synonym Symbols: | NGN2; Atoh4; ngn-2; Math4A; bHLHa8 |
NCBI Protein Information: | neurogenin-2 |
UniProt Protein Name: | Neurogenin-2 |
UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 8; bHLHa8; Protein atonal homolog 4 |
Protein Family: | Neurogenin |
UniProt Gene Name: | NEUROG2 |
UniProt Entry Name: | NGN2_HUMAN |