NEU2 Antibody (PACO45023)
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주문- SKU:
- PACO45023
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NEU2 Antibody (PACO45023) |
Antibody SKU: | PACO45023 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Sialidase-2 protein (171-380AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO45023 at dilution of 1:100. |
Background: | Catalyzes the removal of sialic acid, (N-acetylneuraminic acid, moities from glycoproteins, oligosaccharides and gangliosides. |
Synonyms: | Sialidase-2 (EC 3.2.1.18) (Cytosolic sialidase) (N-acetyl-alpha-neuraminidase 2), NEU2 |
UniProt Protein Function: | NEU2: Hydrolyzes sialylated compounds. Belongs to the glycosyl hydrolase 33 family. |
UniProt Protein Details: | Protein type:EC 3.2.1.18; Hydrolase; Glycan Metabolism - other glycan degradation; Lipid Metabolism - sphingolipid Chromosomal Location of Human Ortholog: 2q37 Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; membrane Molecular Function:exo-alpha-sialidase activity; protein binding Biological Process: ganglioside catabolic process; glycosphingolipid metabolic process; oligosaccharide catabolic process |
NCBI Summary: | This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y3R4 |
NCBI GenInfo Identifier: | 229462907 |
NCBI Gene ID: | 4759 |
NCBI Accession: | Q9Y3R4.2 |
UniProt Secondary Accession: | Q9Y3R4,Q3KNW4, Q6NTB4, |
UniProt Related Accession: | Q9Y3R4 |
Molecular Weight: | 42,254 Da |
NCBI Full Name: | Sialidase-2 |
NCBI Synonym Full Names: | neuraminidase 2 |
NCBI Official Symbol: | NEU2 |
NCBI Official Synonym Symbols: | SIAL2 |
NCBI Protein Information: | sialidase-2 |
UniProt Protein Name: | Sialidase-2 |
UniProt Synonym Protein Names: | Cytosolic sialidase; N-acetyl-alpha-neuraminidase 2 |
Protein Family: | Sialidase |
UniProt Gene Name: | NEU2 |
UniProt Entry Name: | NEUR2_HUMAN |