NELL1 Antibody (PACO45569)
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주문- SKU:
- PACO45569
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NELL1 Antibody (PACO45569) |
Antibody SKU: | PACO45569 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Protein kinase C-binding protein NELL1 protein (160-420AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: NELL1 antibody at 3.47 µg/ml. Lane 1: Mouse liver tissue. Lane 2: Mouse kidney tissue. Lane 3: Mouse spleen tissue. Lane 4: Human placenta tissue. Lane 5: Hela whole cell lysate. Lane 6: Jurkat whole cell lysate. Lane 7: MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 90, 85 kDa. Observed band size: 90, 65, 58, 35 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45569 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO45569 at dilution of 1:100. |
Background: | Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization. |
Synonyms: | Protein kinase C-binding protein NELL1 (NEL-like protein 1) (Nel-related protein 1), NELL1, NRP1 |
UniProt Protein Function: | NELL1: Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 11p15.1 Cellular Component: cytoplasm; nuclear envelope; perinuclear region of cytoplasm Molecular Function:protein binding Biological Process: negative regulation of osteoblast proliferation; nervous system development; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; regulation of gene expression |
NCBI Summary: | This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
UniProt Code: | Q92832 |
NCBI GenInfo Identifier: | 311033486 |
NCBI Gene ID: | 4745 |
NCBI Accession: | Q92832.4 |
UniProt Secondary Accession: | Q92832,Q4VB90, Q4VB91, Q6NSY8, Q9Y472, B2CKC1, |
UniProt Related Accession: | Q92832 |
Molecular Weight: | 84,377 Da |
NCBI Full Name: | Protein kinase C-binding protein NELL1 |
NCBI Synonym Full Names: | neural EGFL like 1 |
NCBI Official Symbol: | NELL1 |
NCBI Official Synonym Symbols: | NRP1; IDH3GL |
NCBI Protein Information: | protein kinase C-binding protein NELL1 |
UniProt Protein Name: | Protein kinase C-binding protein NELL1 |
UniProt Synonym Protein Names: | NEL-like protein 1; Nel-related protein 1 |
Protein Family: | Protein kinase C-binding protein |
UniProt Gene Name: | NELL1 |
UniProt Entry Name: | NELL1_HUMAN |