NDUFA2 Antibody (PACO31588)
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주문- SKU:
- PACO31588
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NDUFA2 Antibody (PACO31588) |
Antibody SKU: | PACO31588 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human NADH dehydrogenase [ubiquinone] 1 α subcomplex subunit 2 protein (4-99AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO31588 at dilution of 1:100. |
Background: | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Synonyms: | NADH dehydrogenase [ubiquinone] 1 α subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit), NDUFA2 |
UniProt Protein Function: | NDUFA2: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
UniProt Protein Details: | Protein type:Mitochondrial; EC 1.6.99.3; Oxidoreductase; EC 1.6.5.3; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 5q31.2 Cellular Component: mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex I Molecular Function:NADH dehydrogenase (ubiquinone) activity Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly Disease: Leigh Syndrome |
NCBI Summary: | The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
UniProt Code: | O43678 |
NCBI GenInfo Identifier: | 297206774 |
NCBI Gene ID: | 4695 |
NCBI Accession: | NP_001171941.1 |
UniProt Secondary Accession: | O43678,Q6IAY8, D6RJD6, |
UniProt Related Accession: | O43678 |
Molecular Weight: | 8,491 Da |
NCBI Full Name: | NADH dehydrogenase |
NCBI Synonym Full Names: | NADH:ubiquinone oxidoreductase subunit A2 |
NCBI Official Symbol: | NDUFA2 |
NCBI Official Synonym Symbols: | B8; CD14; CIB8 |
NCBI Protein Information: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 |
UniProt Protein Name: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 |
UniProt Synonym Protein Names: | Complex I-B8; CI-B8; NADH-ubiquinone oxidoreductase B8 subunit |
Protein Family: | NADH dehydrogenase |
UniProt Gene Name: | NDUFA2 |
UniProt Entry Name: | NDUA2_HUMAN |
Antibodies |
Anti-NDUFA2 Antibody (CAB8136) |
Secondary Antibody |
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