NCALD Antibody (PACO44957)
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주문- SKU:
- PACO44957
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NCALD Antibody (PACO44957) |
Antibody SKU: | PACO44957 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Neurocalcin-delta protein (1-193AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: NCALD antibody at 9.32 µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 22 kDa. Observed band size: 22 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human brain tissue using PACO44957 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO44957 at dilution of 1:100. |
Background: | May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions. |
Synonyms: | Neurocalcin-delta, NCALD |
UniProt Protein Function: | NCALD: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions. Belongs to the recoverin family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 8q22.2 Cellular Component: clathrin coat of trans-Golgi network vesicle; intracellular; cytosol Molecular Function:tubulin binding; protein binding; clathrin binding; calcium ion binding; actin binding; alpha-tubulin binding Biological Process: vesicle-mediated transport; synaptic transmission; regulation of systemic arterial blood pressure; calcium-mediated signaling |
NCBI Summary: | This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | P61601 |
NCBI GenInfo Identifier: | 47606440 |
NCBI Gene ID: | 83988 |
NCBI Accession: | P61601.2 |
UniProt Related Accession: | P61601 |
Molecular Weight: | |
NCBI Full Name: | Neurocalcin-delta |
NCBI Synonym Full Names: | neurocalcin delta |
NCBI Official Symbol: | NCALD |
NCBI Protein Information: | neurocalcin-delta |
UniProt Protein Name: | Neurocalcin-delta |
Protein Family: | Neurocalcin |
UniProt Gene Name: | NCALD |
UniProt Entry Name: | NCALD_HUMAN |