NACA2 Antibody (PACO42146)
- SKU:
- PACO42146
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | NACA2 Antibody (PACO42146) |
| Antibody SKU: | PACO42146 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Nascent polypeptide-associated complex subunit alpha-2 protein (1-215AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: NACA2 antibody at 5µg/ml + 293T whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 24 kDa. Observed band size: 24 kDa. |
| Background: | Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). |
| Synonyms: | Nascent polypeptide-associated complex subunit alpha-2 (Alpha-NAC-like) (Hom s 2.01) (Nascent polypeptide-associated complex subunit alpha-like) (NAC-alpha-like), NACA2, NACAL |
| UniProt Protein Function: | NACA2: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). Belongs to the NAC-alpha family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 17q23.2 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H009 |
| NCBI GenInfo Identifier: | 74733511 |
| NCBI Gene ID: | 342538 |
| NCBI Accession: | Q9H009.1 |
| UniProt Secondary Accession: | Q9H009,Q2VIR9 |
| UniProt Related Accession: | Q9H009 |
| Molecular Weight: | 23,223 Da |
| NCBI Full Name: | Nascent polypeptide-associated complex subunit alpha-2 |
| NCBI Synonym Full Names: | nascent polypeptide associated complex alpha subunit 2 |
| NCBI Official Symbol: | NACA2 |
| NCBI Official Synonym Symbols: | ANAC; NACAL |
| NCBI Protein Information: | nascent polypeptide-associated complex subunit alpha-2 |
| UniProt Protein Name: | Nascent polypeptide-associated complex subunit alpha-2 |
| UniProt Synonym Protein Names: | Alpha-NAC-like; Hom s 2.01; Nascent polypeptide-associated complex subunit alpha-like; NAC-alpha-like |
| Protein Family: | Nascent polypeptide-associated complex |
| UniProt Gene Name: | NACA2 |
| UniProt Entry Name: | NACA2_HUMAN |
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