MYBPC2 Antibody (PACO44478)
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주문- SKU:
- PACO44478
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MYBPC2 Antibody (PACO44478) |
Antibody SKU: | PACO44478 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Myosin-binding protein C, fast-type protein (912-1141AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO44478 at dilution of 1:100. |
Background: | Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. |
Synonyms: | Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform), MYBPC2, MYBPCF |
UniProt Protein Function: | MYBPC2: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family. |
UniProt Protein Details: | Protein type:Myosin-binding Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: cytosol Molecular Function:protein binding; structural constituent of muscle; actin binding Biological Process: cell adhesion; muscle filament sliding |
NCBI Summary: | This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively. [provided by RefSeq, Jul 2012] |
UniProt Code: | Q14324 |
NCBI GenInfo Identifier: | 296439237 |
NCBI Gene ID: | 4606 |
NCBI Accession: | Q14324.2 |
UniProt Secondary Accession: | Q14324,A1L4G9, |
UniProt Related Accession: | Q14324 |
Molecular Weight: | 1141 |
NCBI Full Name: | Myosin-binding protein C, fast-type |
NCBI Synonym Full Names: | myosin binding protein C, fast type |
NCBI Official Symbol: | MYBPC2 |
NCBI Official Synonym Symbols: | MYBPC; MYBPCF |
NCBI Protein Information: | myosin-binding protein C, fast-type; fast MyBP-C; C-protein, skeletal muscle fast isoform; fast-type muscle myosin-binding-protein C |
UniProt Protein Name: | Myosin-binding protein C, fast-type |
UniProt Synonym Protein Names: | C-protein, skeletal muscle fast isoform |
Protein Family: | Myosin-binding protein |
UniProt Gene Name: | MYBPC2 |
UniProt Entry Name: | MYPC2_HUMAN |