MTHFD2L Antibody (PACO41106)
- SKU:
- PACO41106
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MTHFD2L Antibody (PACO41106) |
Antibody SKU: | PACO41106 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 protein (136-268AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: MTHFD2L antibody at 6µg/ml + Mouse lung tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 38, 32, 8, 25, 33 kDa. Observed band size: 14 kDa. |
Background: | mitochondrion, methenyltetrahydrofolate cyclohydrolase activity, methylenetetrahydrofolate dehydrogenase (NAD+) activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, one-carbon metabolic process |
Synonyms: | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 (NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein) (MTHFD2-like) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)], MTHFD2L |
UniProt Protein Function: | MTHFD2L: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.5.1.15; EC 3.5.4.9; Hydrolase; Mitochondrial; OxidoreductaseChromosomal Location of Human Ortholog: 4q13.3Cellular Component: cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrionMolecular Function: methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; methylenetetrahydrofolate dehydrogenase (NADP+) activityBiological Process: 10-formyltetrahydrofolate metabolic process; folic acid metabolic process; histidine biosynthetic process; methionine biosynthetic process; one-carbon metabolic process; purine nucleotide biosynthetic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9H903 |
NCBI GenInfo Identifier: | 222418558 |
NCBI Gene ID: | 441024 |
NCBI Accession: | NP_001138450.1 |
UniProt Secondary Accession: | Q9H903,Q6P079, Q8N560 |
UniProt Related Accession: | Q9H903 |
Molecular Weight: | 32,891 Da |
NCBI Full Name: | probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform 2 |
NCBI Synonym Full Names: | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like |
NCBI Official Symbol: | MTHFD2L |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 |
UniProt Protein Name: | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 |
UniProt Synonym Protein Names: | NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; MTHFD2-like |
Protein Family: | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase |
UniProt Gene Name: | MTHFD2L |
UniProt Entry Name: |