MSRA Antibody (PACO62619)
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주문- SKU:
- PACO62619
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MSRA Antibody (PACO62619) |
Antibody SKU: | PACO62619 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Mitochondrial peptide methionine sulfoxide reductase protein (24-235AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO62619 diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. |
Synonyms: | Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR), MSRA |
UniProt Protein Function: | MSRA: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Belongs to the MsrA Met sulfoxide reductase family. 5 isoforms of the human protein are produced by alternative promoter. |
UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.8.4.11 Chromosomal Location of Human Ortholog: 8p23.1 Cellular Component: actin cytoskeleton; cytoplasm; cytosol; nucleoplasm Molecular Function:peptide-methionine-(S)-S-oxide reductase activity Biological Process: methionine metabolic process; protein modification process; protein repair |
NCBI Summary: | This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
UniProt Code: | Q9UJ68 |
NCBI GenInfo Identifier: | 12230350 |
NCBI Gene ID: | 4482 |
NCBI Accession: | Q9UJ68.1 |
UniProt Secondary Accession: | Q9UJ68,Q52TC4, Q549N4, Q66MI7, E9PAS8, |
UniProt Related Accession: | Q9UJ68 |
Molecular Weight: | 23,627 Da |
NCBI Full Name: | Mitochondrial peptide methionine sulfoxide reductase |
NCBI Synonym Full Names: | methionine sulfoxide reductase A |
NCBI Official Symbol: | MSRA |
NCBI Official Synonym Symbols: | PMSR |
NCBI Protein Information: | mitochondrial peptide methionine sulfoxide reductase |
UniProt Protein Name: | Mitochondrial peptide methionine sulfoxide reductase |
UniProt Synonym Protein Names: | Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase; Protein-methionine-S-oxide reductase; PMSR |
Protein Family: | Mitochondrial peptide methionine sulfoxide reductase |
UniProt Gene Name: | MSRA |
UniProt Entry Name: | MSRA_HUMAN |
Antibodies | ELISA Kits |
Anti-MSRA Antibody (CAB12464) | Human Mitochondrial peptide methionine sulfoxide reductase / MSRA ELISA Kit |
Anti-MSRA Antibody (CAB6389) | |
MSRA Antibody (PACO10627) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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