MSC Antibody (PACO49778)
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주문- SKU:
- PACO49778
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MSC Antibody (PACO49778) |
Antibody SKU: | PACO49778 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Musculin protein (3-143AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human lymph node tissue using PACO49778 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO49778 at dilution of 1:100. |
Background: | Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation. |
Synonyms: | Musculin (Activated B-cell factor 1) (ABF-1) (Class A basic helix-loop-helix protein 22) (bHLHa22), MSC, ABF1 BHLHA22 |
UniProt Protein Function: | MSC: Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 8q21 Cellular Component: nucleoplasm; nucleus Molecular Function:transcription corepressor activity; transcription factor activity Biological Process: transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60682 |
NCBI GenInfo Identifier: | 15214091 |
NCBI Gene ID: | 9242 |
NCBI Accession: | O60682.2 |
UniProt Secondary Accession: | O60682,O75946, Q53XZ2, Q9BRE7, |
UniProt Related Accession: | O60682 |
Molecular Weight: | 22,068 Da |
NCBI Full Name: | Musculin |
NCBI Synonym Full Names: | musculin |
NCBI Official Symbol: | MSC |
NCBI Official Synonym Symbols: | ABF1; MYOR; ABF-1; bHLHa22 |
NCBI Protein Information: | musculin |
UniProt Protein Name: | Musculin |
UniProt Synonym Protein Names: | Activated B-cell factor 1; ABF-1; Class A basic helix-loop-helix protein 22; bHLHa22 |
Protein Family: | Musculin |
UniProt Gene Name: | MSC |
UniProt Entry Name: | MUSC_HUMAN |
Antibodies | ELISA Kits |
MSC Antibody (PACO01120) | Human MSC (Musculin) ELISA Kit (HUFI05044) |
Musculin Colorimetric Cell-Based ELISA |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |