MRPS35 Antibody (PACO10615)
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주문- SKU:
- PACO10615
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MRPS35 Antibody (PACO10615) |
Antibody SKU: | PACO10615 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human MRPS35 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | mitochondrial ribosomal protein S35;MRPS35;DKFZp762P093;HDCMD11P;MDS023;MGC104278;MRP-S28;MRPS28 ; |
UniProt Protein Function: | TMEPAI: Involved in down-regulation of the androgen receptor (AR). Enhances ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4. Belongs to the PMEPA1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 20q13.31-q13.33 Cellular Component: Golgi membrane; early endosome membrane; integral to membrane; plasma membrane; endosome membrane Molecular Function:protein binding; WW domain binding Biological Process: transforming growth factor beta receptor signaling pathway; androgen receptor signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway |
NCBI Summary: | This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | P82673 |
NCBI GenInfo Identifier: | 364023812 |
NCBI Gene ID: | 56937 |
NCBI Accession: | NP_001242905.1 |
UniProt Secondary Accession: | P82673,Q5TDR6, Q8NER4, Q96B72, Q9UJD3, |
UniProt Related Accession: | Q969W9 |
Molecular Weight: | |
NCBI Full Name: | protein TMEPAI isoform d |
NCBI Synonym Full Names: | prostate transmembrane protein, androgen induced 1 |
NCBI Official Symbol: | PMEPA1 |
NCBI Official Synonym Symbols: | STAG1; TMEPAI |
NCBI Protein Information: | protein TMEPAI; solid tumor-associated 1 protein; transmembrane, prostate androgen induced RNA; prostate transmembrane protein androgen induced 1 |
UniProt Protein Name: | Protein TMEPAI |
UniProt Synonym Protein Names: | Prostate transmembrane protein androgen induced 1; Solid tumor-associated 1 protein; Transmembrane prostate androgen-induced protein |
Protein Family: | Protein |
UniProt Gene Name: | PMEPA1 |
UniProt Entry Name: | PMEPA_HUMAN |