MRC1 Antibody (PACO28326)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO28326
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MRC1 Antibody (PACO28326) |
Antibody SKU: | PACO28326 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Macrophage mannose receptor 1 protein (655-1213AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. |
Synonyms: | Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206), MRC1, CLEC13D CLEC13DL MRC1L1 |
UniProt Protein Function: | MRC1: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc. Chromosomal Location of Human Ortholog: 10p12.33 Cellular Component: endosome membrane; integral to plasma membrane; plasma membrane Molecular Function:protein binding; receptor activity; transmembrane receptor activity Biological Process: receptor-mediated endocytosis |
NCBI Summary: | The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015] |
UniProt Code: | P22897 |
NCBI GenInfo Identifier: | 126730 |
NCBI Gene ID: | 4360 |
NCBI Accession: | P22897.1 |
UniProt Secondary Accession: | P22897,Q5VSJ2, Q5VSK2, A5PKW3, |
UniProt Related Accession: | P22897 |
Molecular Weight: | 166kDa |
NCBI Full Name: | Macrophage mannose receptor 1 |
NCBI Synonym Full Names: | mannose receptor C-type 1 |
NCBI Official Symbol: | MRC1 |
NCBI Official Synonym Symbols: | MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1 |
NCBI Protein Information: | macrophage mannose receptor 1 |
UniProt Protein Name: | Macrophage mannose receptor 1 |
UniProt Synonym Protein Names: | C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human mannose receptor; hMR; Macrophage mannose receptor 1-like protein 1; CD_antigen: CD206 |
Protein Family: | Macrophage mannose receptor |
UniProt Gene Name: | MRC1 |