Mouse PTX2 Recombinant Protein (RPPB4335)

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SKU:
RPPB4335
Product type:
Recombinant Protein
Size:
10ug
Species:
Mouse
Target:
PTX2
Synonyms:
Serum amyloid P-component
Synonyms:
Apcs
Source:
HEK293 Cells
Uniprot:
P12246
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Description

Product Name:Mouse PTX2 Recombinant Protein
Product Code:RPPB4335
Size:10µg
Species:Mouse
Target:PTX2
Synonyms:Serum amyloid P-component, SAP, Apcs, Sap, Ptx2.
Source:HEK293 Cells
Physical Appearance:Sterile Filtered clear solution.
Formulation:PTX2 protein solution (0.25mg/ml) contains 10% glycerol in Phosphate Buffered Saline (pH 7.4).
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:QTDLKRKVFV FPRESETDHV KLIPHLEKPL QNFTLCFRTY SDLSRSQSLF SYSVKGRDNE LLIYKEKVGE YSLYIGQSKV TVRGMEEYLS PVHLCTTWES SSGIVEFWVN GKPWVKKSLQ REYTVKAPPS IVLGQEQDNY GGGFQRSQSF VGEFSDLYMW DYVLTPQDIL FVYRDSPVNP NILNWQALNY EINGYVVIRP RVWDHHHHHH

PTX-2 or Pentraxin-2 is a phylogenetically conserved protein, commonly moving with homopentameric blood protein or with a protein that recognizes receptors of the innate immune system. The protein’s specific binding abilities may show that PTX-2 is specially bound in sites where injury accrued, therefore helps to eliminate damaged tissue by ways that are not phlogistics.

PTX2 Mouse Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 210 amino acids (21-224 a.a) and having a molecular mass of 24.6kDa. (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). PTX2 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:APCS: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. Belongs to the pentaxin family.Protein type: Secreted; Secreted, signal peptide; ChaperoneCellular Component: extracellular matrix; extracellular space; protein complex; extracellular region; nucleusMolecular Function: metal ion binding; complement component C1q binding; virion binding; calcium ion binding; carbohydrate bindingBiological Process: negative regulation of virion penetration into host cell; innate immune response; protein complex assembly; negative regulation of monocyte differentiation; negative regulation of viral reproduction
UniProt Protein Details:
NCBI Summary:
UniProt Code:P12246
NCBI GenInfo Identifier:134198
NCBI Gene ID:0
NCBI Accession:P12246.2
UniProt Secondary Accession:P12246
UniProt Related Accession:P12246
Molecular Weight:
NCBI Full Name:Serum amyloid P-component
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:Serum amyloid P-component
UniProt Synonym Protein Names:
Protein Family:S-layer protein
UniProt Gene Name:Apcs  
UniProt Entry Name:SAMP_MOUSE
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