Mouse PRDX2 Recombinant Protein (RPPB2177)

(No reviews yet) Write a Review

제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.

주문
SKU:
RPPB2177
Product type:
Recombinant Protein
Size:
10ug
Species:
Mouse
Target:
PRDX2
Synonyms:
PRDX2
Synonyms:
Peroxiredoxin-2 (EC:111115)
Synonyms:
TSA
Synonyms:
Thioredoxin peroxidase 1
Source:
Escherichia Coli
Uniprot:
Q61171
€0.00
Frequently bought together:

Description

Product Name:Mouse PRDX2 Recombinant Protein
Product Code:RPPB2177
Size:10µg
Species:Mouse
Target:PRDX2
Synonyms:PRDX2, Peroxiredoxin-2 (EC:1.11.1.15), TSA, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thiol-specific antioxidant protein, Prdx2, Tdpx1, Tpx.  
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:PRDX2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% Glycerol 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMASGNA QIGKSAPDFT ATAVVDGAFK EIKLSDYRGK YVVLFFYPLD FTFVCPTEII AFSDHAEDFR KLGCEVLGVS VDSQFTHLAW INTPRKEGGL GPLNIPLLAD VTKSLSQNYG VLKNDEGIAY RGLFIIDAKG VLRQITVNDL PVGRSVDEAL RLVQAFQYTD EHGEVCPAGW KPGSDTIKPN VDDSKEYFSK HN
Biological Activity:Specific activity is > 700 pmol/min/ug, Activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute. 

PRDX2 is part of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. PRDX2 takes part as an antioxidant protective role in cells, and contributes to the antiviral activity of CD8(+) T-cells. PRDX2 has proliferative effect in cancer development or progression. If PRDX2 protection is insufficient against peroxidases, the DNA damage results in neurological disease such as Alzheimer's or DNA damage leading to cancer.

PRDX2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 222 amino acids (1-198 a.a) and having a molecular mass of 24.3kDa. PRDX2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q61171
NCBI GenInfo Identifier:2499469
NCBI Gene ID:21672
NCBI Accession:Q61171.3
UniProt Secondary Accession:Q61171,O88376, Q60796, Q9CWJ4, Q9DB49
UniProt Related Accession:Q61171
Molecular Weight:21,779 Da
NCBI Full Name:Peroxiredoxin-2
NCBI Synonym Full Names:peroxiredoxin 2
NCBI Official Symbol:Prdx2  
NCBI Official Synonym Symbols:TR; PRP; TPx; TSA; TDX1; NkefB; PrxII; TPx-B; Tdpx1; Torin; Band-8; AL022839  
NCBI Protein Information:peroxiredoxin-2
UniProt Protein Name:Peroxiredoxin-2
UniProt Synonym Protein Names:Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1
Protein Family:Peroxiredoxin
UniProt Gene Name:Prdx2  
UniProt Entry Name:
View AllClose

Related Products