GenieFluor 647 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0498)

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SKU:
AGEL0498
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M5/114
Conjugation:
AF 647
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The Mouse MHC II (I-A/I-E) Monoclonal Antibody (AF647 Conjugated) (M5/114) is a powerful tool for researchers studying the major histocompatibility complex class II (MHC II) molecules in mice. This monoclonal antibody, specifically conjugated with AF647, is designed for use in immunology studies, particularly for analyzing antigen presentation and immune responses.MHC II molecules are essential components of the immune system, playing a crucial role in presenting antigens to T cells and initiating adaptive immune responses. The M5/114 antibody targets the I-A and I-E alleles of MHC II, allowing for specific detection and analysis of these molecules in mouse samples. Its conjugation with AF647 enables fluorescence-based detection methods, making it suitable for applications such as flow cytometry and immunofluorescence.

By using the Mouse MHC II (I-A/I-E) Monoclonal Antibody (AF647 Conjugated) (M5/114), researchers can gain valuable insights into the function and expression of MHC II molecules in mouse models. This antibody facilitates the investigation of immune system dynamics, antigen presentation pathways, and the role of MHC II in various disease conditions. Overall, it serves as a valuable tool for advancing understanding in immunology research and contributes to the development of novel strategies for immune-related disorders.

Product Title:GenieFluor 647 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0498
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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