PE Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1282)

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SKU:
AGEL1282
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
IM7
Conjugation:
PE
Frequently bought together:

Description

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PE Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse-Human CD44 Monoclonal Antibody (PE Conjugated, clone IM7) offered by AssayGenie (Product code: AGEL1282) is a high-quality antibody specifically designed for researchers working with CD44, a cell surface glycoprotein involved in cell adhesion and migration processes. This monoclonal antibody, derived from hybridoma cells, is conjugated to Phycoerythrin (PE) for easy detection and analysis in flow cytometry and other fluorescence-based assays.CD44, a multifunctional transmembrane glycoprotein, plays crucial roles in cell-cell interactions, cell adhesion, and signaling cascades related to cellular processes. The IM7 monoclonal antibody targets both murine and human CD44 isoforms, making it versatile for studies involving various cell types and tissues. Its PE conjugation allows for sensitive and specific detection of CD44 expression levels, aiding in the characterization of cell populations and understanding their behavior in different experimental settings.

Research areas such as immunology, cancer biology, stem cell biology, and regenerative medicine can benefit from this monoclonal antibody by enabling precise identification and analysis of CD44-expressing cells. By using the IM7 monoclonal antibody, researchers can further explore the functional roles of CD44 in processes like immune cell activation, tumor progression, and tissue regeneration, paving the way for new insights and potential therapeutic strategies.Overall, the Mouse-Human CD44 Monoclonal Antibody (PE Conjugated, clone IM7) from AssayGenie provides a powerful tool for investigating the intricate functions of CD44 in cellular physiology and disease pathogenesis, supporting cutting-edge research endeavors in diverse scientific fields.

Product Title:PE Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1282
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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