Biotin Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL0305)

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SKU:
AGEL0305
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rat
Isotype:
IgG2b
Clone:
M1/70
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

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Biotin Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse/Human CD11b Monoclonal Antibody (Biotin Conjugated) - M1/70 (AGEL0305) offered by AssayGenie is a versatile tool for immunology and cell biology research. This antibody is designed to specifically target CD11b, a cell surface marker involved in various immune processes. With its biotin conjugation, this antibody enables easy detection and analysis in experimental setups that require biotin-streptavidin detection systems.CD11b, also known as integrin alpha M, is a key receptor expressed on the surface of monocytes, macrophages, and neutrophils. It plays crucial roles in mediating cell adhesion, migration, and phagocytosis, making it an essential marker for studying immune cell function.

By targeting CD11b, researchers can explore the dynamics of immune cell interactions, inflammatory responses, and immune cell activation in both mouse and human samples.This monoclonal antibody, produced using advanced technology and rigorous quality control measures, ensures high specificity and sensitivity in experiments such as flow cytometry, immunohistochemistry, and immunoprecipitation. Researchers can rely on the precision and accuracy of the Mouse/Human CD11b Monoclonal Antibody - M1/70 (AGEL0305) to advance their understanding of immune responses, inflammatory pathways, and immune cell behavior in health and disease states.

Product Title:Biotin Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL0305
Size:25µg, 100µg
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Biotin Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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