APC Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL1106)

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SKU:
AGEL1106
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M1/70
Conjugation:
APC
Frequently bought together:

Description

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APC Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse Human CD11b Monoclonal Antibody (APC-Conjugated, M1/70) from AssayGenie (AGEL1106) is a cutting-edge immunology tool designed for precise detection and analysis of CD11b, a pivotal cell surface antigen involved in immune response modulation. This high-quality monoclonal antibody, engineered for use with both mouse and human samples, specifically targets the CD11b protein, allowing researchers to gain insights into its expression and function in a variety of cell types.CD11b, also known as integrin alpha-M, is a key receptor involved in leukocyte adhesion and migration, playing a crucial role in inflammatory responses, phagocytosis, and immune cell activation.

By utilizing the CD11b Monoclonal Antibody (APC-Conjugated, M1/70), researchers can delve into the intricate mechanisms underlying immune regulation, with potential applications in studies related to inflammation, infection, and autoimmune diseases.With its validated performance and versatility in flow cytometry applications, this antibody is an indispensable tool for scientists engaged in immunology research, drug development, and therapeutic investigations targeting immune-related disorders. Unlock the potential of CD11b analysis with the precision and reliability offered by this state-of-the-art monoclonal antibody from AssayGenie.

Product Title:APC Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL1106
Size:25µg, 100µg
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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