PE/Cyanine7 Anti-Mouse F4/80 Antibody [CI:A3-1] (AGEL0571)

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SKU:
AGEL0571
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
CI:A3-1
Conjugation:
PE/Cy7
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse F4/80 Antibody [CI:A3-1]

The Mouse F4/80 Monoclonal Antibody PE-Cyanine7 Conjugated (CI: A3-1) (AGEL0571) from Assay Genie is a powerful tool for researchers studying macrophages and immune responses in mice. This antibody specifically targets the F4/80 protein, a well-known marker for mouse macrophages, allowing for precise detection and analysis in various experimental settings.Macrophages are key players in the immune system, involved in processes such as phagocytosis, antigen presentation, and inflammatory responses. The F4/80 protein is widely used as a marker to identify these cells in tissue samples, making this antibody an essential component for studies in immunology, inflammation, and cancer research using mouse models.

By utilizing the Mouse F4/80 Monoclonal Antibody PE-Cyanine7 Conjugated (CI: A3-1) (AGEL0571), researchers can gain valuable insights into the role of macrophages in various physiological and pathological conditions. Its high specificity and reliable performance make it an ideal choice for studies aimed at understanding the complex interactions between macrophages and the immune system in mouse models.

Product Title:PE/Cyanine7 Anti-Mouse F4/80 Antibody [CI:A3-1]
SKU:AGEL0571
Size:25µg, 100µg
Clone No:CI:A3-1
Synonyms:Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q61549
Gene ID:13733
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

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