FITC Anti-Mouse CD86 Antibody [GL-1] (AGEL0552)

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SKU:
AGEL0552
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
GL-1
Conjugation:
FITC
Frequently bought together:

Description

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FITC Anti-Mouse CD86 Antibody [GL-1]

The Mouse CD86 Monoclonal Antibody (FITC Conjugated, GL-1) is an essential tool for researchers investigating immune responses and cell signaling pathways. This antibody, derived from hybridoma cells, specifically targets the CD86 protein found on the surface of antigen-presenting cells.CD86, also known as B7-2, is a co-stimulatory molecule involved in T cell activation and immune regulation. By binding to CD86, this monoclonal antibody enables the detection and analysis of CD86 expression in various cell types, making it an invaluable asset for studies in immunology, vaccine development, and autoimmune diseases.

The FITC conjugation of this antibody allows for easy visualization and quantification of CD86 expression through flow cytometry and fluorescent microscopy techniques. Its high specificity and sensitivity ensure reliable and reproducible results in experimental settings.Overall, the Mouse CD86 Monoclonal Antibody (FITC Conjugated, GL-1) is a versatile reagent that aids in understanding the complex interactions of the immune system, paving the way for advancements in immunotherapy, vaccine design, and targeted treatment strategies.

Product Title:FITC Anti-Mouse CD86 Antibody [GL-1]
SKU:AGEL0552
Size:25µg, 100µg
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P42082
Gene ID:12524
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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