PE/Cyanine7 Anti-Mouse CD80 Antibody [16-10A1] (AGEL0536)

(No reviews yet) Write a Review
SKU:
AGEL0536
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine7 Anti-Mouse CD80 Antibody [16-10A1]

The Mouse CD80 Monoclonal Antibody PE/Cyanine7 Conjugated (16-10A1) is a powerful tool for researchers studying immune responses and immune cell interactions. This antibody specifically targets CD80, a critical co-stimulatory molecule involved in T cell activation and immune regulation.With its PE/Cyanine7 conjugation, this antibody offers the advantage of dual fluorescence labeling, allowing for multiplex analysis in flow cytometry and immunofluorescence assays. The 16-10A1 antibody is derived from mouse monoclonal sources, ensuring high specificity and sensitivity in detecting CD80 expression in mouse samples.CD80, also known as B7-1, is a key player in the complex network of immune checkpoints that modulate T cell activation and tolerance.

By targeting CD80 with this conjugated monoclonal antibody, researchers can gain valuable insights into immune signaling pathways, immune cell activation, and regulatory mechanisms.This antibody is a valuable tool for investigating immune responses in various experimental settings, from basic immunology research to studies on autoimmune diseases, infectious diseases, and cancer immunotherapy. With its high quality and specificity, the Mouse CD80 Monoclonal Antibody PE/Cyanine7 Conjugated (16-10A1) is an essential reagent for advancing our understanding of immune system function and developing novel therapeutic approaches.

Product Title:PE/Cyanine7 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL0536
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Cyanine7 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

0 Reviews

View AllClose

Related Products