Biotin Anti-Mouse CD73 Antibody [TY/23] (AGEL0329)

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SKU:
AGEL0329
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
TY/23
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

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Biotin Anti-Mouse CD73 Antibody [TY/23]

The Mouse CD73 Monoclonal Antibody (Biotin Conjugated) TY-23 (AGEL0329) is a specialized tool designed for research involving CD73, an ecto-5'-nucleotidase enzyme known for its role in purinergic signaling and immune regulation. This monoclonal antibody, conjugated with biotin for enhanced detection capabilities, is derived from a mouse source and exhibits high specificity and sensitivity in binding to CD73 protein in mouse samples.CD73, also known as Cluster of Differentiation 73, is a key player in the conversion of extracellular adenosine monophosphate (AMP) to adenosine, a process that modulates immune responses, inflammation, and tissue repair. By targeting CD73, researchers can explore its functions in various cellular processes, including immune cell regulation, cancer progression, and vascular biology.

The TY-23 monoclonal antibody allows for precise detection and localization of CD73 in tissues and cell cultures, making it an invaluable tool for immunohistochemistry, flow cytometry, and other experimental techniques. Its application extends to studies focusing on adenosine-mediated signaling pathways, immunotherapy development, and elucidating the role of CD73 in pathophysiological conditions such as inflammation, ischemia, and cancer.By utilizing the Mouse CD73 Monoclonal Antibody (Biotin Conjugated) TY-23 (AGEL0329), researchers can gain insights into the complex interplay of purinergic signaling and immune regulation, advancing our understanding of CD73 biology and its therapeutic implications in various disease contexts.

Product Title:Biotin Anti-Mouse CD73 Antibody [TY/23]
SKU:AGEL0329
Size:25µg, 100µg
Clone No:TY/23
Synonyms:5'-nucleotidase;Nt5e;5'-NT;Ecto-5'-nucleotidase;CD73;Nt5; Nte;Nt5e;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q61503
Gene ID:23959
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD73 (ecto-5`-nucleotidase) is a 69 kD GPI-anchored surface protein. In mice, expression of CD73 in bone marrow is restricted to CD11b+ myeloid cells. In spleen, it is largely expressed on T cells.

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