The Mouse CD71 Monoclonal Antibody (Alexa Fluor 488 Conjugated, R17-217.1.3-TIB-219, AGEL0340) offered by Assay Genie is a cutting-edge tool for researchers working with CD71, a cell surface marker associated with iron metabolism and cell proliferation. This antibody, specifically designed for mouse samples, is conjugated with Alexa Fluor 488 for fluorescence-based detection methods, such as immunofluorescence and flow cytometry.CD71, also known as transferrin receptor 1, plays a crucial role in cellular iron uptake and is often upregulated in rapidly dividing cells. By targeting CD71 with this highly specific monoclonal antibody, researchers can accurately detect and quantify CD71 expression in various cell types and tissues.
This makes it an invaluable tool for studies related to cell biology, cancer research, and iron metabolism.Understanding the dynamics of CD71 expression and its functional implications can provide insights into cellular processes such as proliferation, differentiation, and iron homeostasis. With the Mouse CD71 Monoclonal Antibody (Alexa Fluor 488 Conjugated) from Assay Genie, researchers can delve deeper into the role of CD71 in their specific research areas, paving the way for new discoveries and therapeutic interventions.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q62351
Gene ID:
22042
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.