The Mouse CD5 Monoclonal Antibody (AF488 Conjugated) 53-7.3 (AGEL1967) is a powerful tool for immunological research, specifically targeting the CD5 protein present on the surface of immune cells. This monoclonal antibody has been engineered for optimal performance in various experimental applications such as flow cytometry, immunofluorescence, and immunohistochemistry.CD5, a glycoprotein found on T cells and some B cells, plays a crucial role in regulating immune responses and modulating cell signaling pathways. The AF488 conjugated version of the 53-7.3 antibody allows for precise and sensitive detection of CD5 expression in cell populations, enabling researchers to investigate immune cell function and interactions in depth.
The high specificity and sensitivity of this monoclonal antibody make it an indispensable tool for studying immune system dynamics, immune cell development, and immune-mediated diseases. Researchers seeking to unravel the complexities of immune regulation and cellular responses will benefit greatly from the precision and reliability offered by the Mouse CD5 Monoclonal Antibody (AF488 Conjugated) 53-7.3 (AGEL1967).
Product Title:
GenieFluor 488 Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL1967
Size:
25µg, 100µg
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.