PE/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1405)

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SKU:
AGEL1405
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
RA3.3A 1/6.1
Conjugation:
PE/Cy5.5
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R (B220) Monoclonal Antibody - PE/Cyanine5.5 Conjugated (RA3-6B2) is a powerful tool for immunological research, specifically targeting the CD45R (B220) marker expressed on B cells and subsets of T cells. This monoclonal antibody, conjugated with PE/Cyanine5.5, offers high sensitivity and specificity in flow cytometry and immunofluorescence applications. CD45R (B220) is a well-known cell surface marker that plays a crucial role in B cell development and activation. By targeting this marker, researchers can accurately identify and analyze B cell populations in various tissues and understand their roles in immune responses.

This antibody is ideal for studying autoimmune diseases, B cell malignancies, and immune cell dynamics in immune-mediated disorders.With its high reactivity and specificity, the Mouse CD45R (B220) Monoclonal Antibody - PE/Cyanine5.5 Conjugated (RA3-6B2) provides valuable insights into the function and regulation of B cell subsets, making it an indispensable tool for immunologists and researchers studying adaptive immune responses.

Product Title:PE/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1405
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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