GenieFluor 647 Anti-Mouse CD45 Antibody [30-F11] (AGEL1676)

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SKU:
AGEL1676
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
30-F11
Conjugation:
AF 647
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD45 Antibody [30-F11]

The Mouse CD45 Monoclonal Antibody (AF647 Conjugated, 30-F11) is a specialized tool for researchers studying immune cells within the mouse model system. This antibody, labeled with AF647 for fluorescent detection, specifically targets the CD45 protein, a key marker for immune cell identification and characterization.CD45, also known as leukocyte common antigen, is a critical component of immune cell function, playing a vital role in signal transduction and cell activation. With this monoclonal antibody, researchers can accurately visualize and analyze CD45 expression in various cell types, aiding in the understanding of immune responses in health and disease.

This antibody is well-suited for flow cytometry and immunofluorescence applications, allowing for precise and sensitive detection of CD45-expressing cells. Its high specificity and sensitivity make it an essential tool for immunologists, cancer researchers, and experts in the fields of inflammation and autoimmune disorders.By utilizing the Mouse CD45 Monoclonal Antibody (AF647 Conjugated, 30-F11), researchers can gain valuable insights into the behavior and function of immune cells in mouse model systems, ultimately contributing to advancements in immunology research and potential therapeutic interventions.

Product Title:GenieFluor 647 Anti-Mouse CD45 Antibody [30-F11]
SKU:AGEL1676
Size:25µg, 100µg
Clone No:30-F11
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P06800
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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