The Mouse CD45.2 Monoclonal Antibody PE-Cyanine7 Conjugated (104-2-AG) is a cutting-edge tool for researchers working in the field of immunology and cell biology. This antibody, featuring a unique PE-Cyanine7 conjugation, specifically targets the CD45.2 protein found on the surface of mouse immune cells. With its high selectivity and sensitivity, it allows for precise detection and analysis of CD45.2 in a variety of cell types.CD45.2 is a key protein involved in immune cell signaling and activation, making it a crucial marker for studying immune responses and cell function. By using this monoclonal antibody, researchers can gain valuable insights into the role of CD45.
2 in immune system modulation, inflammation, and disease progression. Its fluorescent conjugation enables easy visualization and tracking of CD45.2 expression, facilitating experiments in flow cytometry, immunofluorescence, and other analytical techniques.Whether investigating immune cell dynamics, inflammatory processes, or immune-related diseases, the Mouse CD45.2 Monoclonal Antibody PE-Cyanine7 Conjugated (104-2-AG) from Assay Genie provides a powerful and reliable tool for advancing scientific research and uncovering new discoveries in the field of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
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