PE Anti-Mouse CD45.1 Antibody [A20] (AGEL1949)

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SKU:
AGEL1949
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE Anti-Mouse CD45.1 Antibody [A20]

The Mouse CD45.1 Monoclonal Antibody PE Conjugated (A20) is a powerful tool for researchers studying immune cells in mouse models. This antibody specifically targets the CD45.1 antigen, a marker for certain subsets of immune cells, including T cells and B cells. The PE conjugation allows for easy and efficient detection of CD45.1-positive cells using flow cytometry, a widely used technique in immunology research. With the A20 clone, researchers can confidently identify and analyze immune cell populations in mouse samples.The CD45.1 antigen is essential for understanding immune cell development, activation, and function in mouse models.

By using this monoclonal antibody, researchers can gain valuable insights into the role of specific immune cell subsets in various immune responses, autoimmune diseases, and tumor immunity in preclinical studies.Overall, the Mouse CD45.1 Monoclonal Antibody PE Conjugated (A20) is a reliable tool for researchers aiming to elucidate the intricate mechanisms of the immune system in mouse models, paving the way for advancements in immunology and potentially leading to new therapeutic strategies for immune-related diseases.

Product Title:PE Anti-Mouse CD45.1 Antibody [A20]
SKU:AGEL1949
Size:25µg, 100µg
Clone No:A20
Synonyms:Ly-5;L-CA;T200;CD45;Ptprc;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45.1 is an alloantigen of CD45, expressed by Ly5.1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in mice that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell types. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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