The Mouse CD335 Monoclonal Antibody (APC conjugated) 29A1-4 (AG-EL1938) is a powerful tool for researchers studying natural killer cell receptors and their role in immune responses. This antibody specifically targets the CD335 protein, also known as NKp46, which is a key receptor involved in the recognition and killing of infected or abnormal cells by natural killer cells.By utilizing this APC-conjugated monoclonal antibody, researchers can easily detect and analyze CD335 expression in various cell types, providing valuable insights into the function and activity of natural killer cells in the immune system. The high specificity and sensitivity of this antibody make it an ideal choice for flow cytometry applications, allowing for precise identification and characterization of CD335-expressing cells.The CD335 Monoclonal Antibody 29A1-4 is rigorously validated for use in immunological research, making it a reliable tool for investigating the mechanisms underlying immune responses, infectious diseases, and cancer.
Its ability to target CD335 with high accuracy and efficiency makes it a valuable asset for studies focused on understanding the complex interactions between natural killer cells and their targets in both health and disease.Overall, this APC-conjugated monoclonal antibody offers researchers a unique opportunity to delve deeper into the functions of natural killer cells and the intricate pathways involved in immune surveillance and defense mechanisms. With its proven efficacy and versatility, the Mouse CD335 Monoclonal Antibody (APC conjugated) 29A1-4 (AG-EL1938) is an essential resource for those seeking to advance their knowledge of immune regulation and cellular interactions in the context of host defense and disease pathology.
Product Title:
APC Anti-Mouse CD335 Antibody [29A1.4]
SKU:
AGEL1938
Size:
25µg, 100µg
Clone No:
29A1.4
Synonyms:
Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
APC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q8C567
Gene ID:
17086
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.