The Mouse CD3 Monoclonal Antibody PE/Cyanine7 Conjugated (17A2) is a cutting-edge tool designed for researchers studying immune responses and T cell biology. This antibody is specifically engineered to target the CD3 protein found on the surface of T cells, a key player in initiating immune responses and coordinating immune cell activities.By conjugating PE and Cyanine7 to the antibody, it enables precise detection and analysis of CD3 in flow cytometry applications. This allows for the identification and characterization of T cells in various biological samples, offering valuable insights into immune system function and responses.
The 17A2 antibody is rigorously validated for specificity and performance, ensuring reliable and reproducible results in experimental settings. Its high reactivity with mouse samples makes it an essential tool for immunology research, including studies on autoimmune diseases, infectious diseases, and immunotherapy development.Overall, the Mouse CD3 Monoclonal Antibody PE/Cyanine7 Conjugated (17A2) is a versatile and powerful reagent that can significantly advance understanding of T cell biology and immune responses, providing researchers with a valuable asset in their quest to unravel the complexities of the immune system.
Product Title:
PE/Cyanine7 Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL0660
Size:
25µg, 100µg
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.