Purified Anti-Mouse CD3 Antibody [17A2] (AGEL0096)

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SKU:
AGEL0096
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
17A2
Conjugation:
Unconjugated
Applications:
FC
IHC
IP
Frequently bought together:

Description

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Purified Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody (17A2) is an essential tool for researchers studying immune responses in mouse models. This monoclonal antibody, clone 17A2, recognizes the CD3 antigen, a key marker of T cells and a crucial component of the T cell receptor complex. By targeting CD3, this antibody allows for the specific detection and analysis of T cells in various experimental settings.CD3 is a vital protein involved in T cell activation and signaling, making it a central player in the adaptive immune response. The Mouse CD3 Monoclonal Antibody (17A2) provides researchers with a reliable tool to study T cell function, proliferation, and differentiation in mouse models of immunology, infectious diseases, and autoimmune disorders.

With its high specificity and sensitivity, this monoclonal antibody is suitable for a range of applications, including flow cytometry, immunohistochemistry, and functional assays. Its ability to bind specifically to the CD3 antigen facilitates accurate and reproducible results, aiding in the understanding of T cell biology and immune system function.Ideal for immunologists, cell biologists, and researchers interested in T cell biology, the Mouse CD3 Monoclonal Antibody (17A2) is a valuable resource for investigating the intricate mechanisms of immune responses in mouse models.

Product Title:Purified Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0096
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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