PE/Cyanine5 Anti-Mouse CD3ε Antibody [145-2C11] (AGEL1325)

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SKU:
AGEL1325
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3-Epsilon Monoclonal Antibody (PE/Cyanine5 Conjugated) 145-2C11 (AGEL1325) offered by Assay Genie is a cutting-edge tool for researchers interested in studying T-cell biology and immune responses in mice. This antibody specifically targets the CD3-Epsilon protein, a crucial component of the T-cell receptor complex that plays a central role in T-cell activation and signaling.Utilizing the powerful combination of PE and Cyanine5 fluorophores, this conjugated antibody allows for robust and sensitive detection of CD3-Epsilon in flow cytometry and immunofluorescence applications. Its high specificity and binding affinity make it an excellent choice for profiling T-cell populations, monitoring T-cell activation, and dissecting immune responses in mouse models.

With the ability to accurately identify and quantify CD3-Epsilon-expressing cells, researchers can gain deeper insights into the dynamics of T-cell function in various physiological and pathological conditions. From investigating immune responses to infectious agents to studying autoimmune diseases and cancer immunology, this antibody is a valuable tool for unraveling the complexities of the immune system in preclinical research.Trust in the Mouse CD3-Epsilon Monoclonal Antibody (PE/Cyanine5 Conjugated) 145-2C11 (AGEL1325) from Assay Genie to enhance your studies and drive discoveries in immunology, cancer research, and beyond.

Product Title:PE/Cyanine5 Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL1325
Size:25µg, 100µg
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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