The Mouse CD3-Epsilon Monoclonal Antibody PE/Cyanine5.5 Conjugated (145-2C11) from AssayGenie (AGEL1327) is a cutting-edge tool designed for immunological research. This antibody specifically targets the CD3-Epsilon protein, a crucial component of the T-cell receptor complex responsible for T-cell activation and function.This high-quality monoclonal antibody, conjugated with PE/Cyanine5.5, allows for easy and precise detection of CD3-Epsilon in samples, streamlining experimental workflows. Its specificity and sensitivity make it an ideal choice for flow cytometry experiments, immunofluorescence assays, and other immunological techniques aimed at studying T-cell biology and activation mechanisms.
Researchers in the field of immunology, cancer biology, and autoimmune disorders will find the Mouse CD3-Epsilon Monoclonal Antibody PE/Cyanine5.5 Conjugated (145-2C11) invaluable for investigating T-cell responses, immune system function, and potential therapeutic targets. Trust AssayGenie's expertise and quality products to advance your research in understanding immune regulation and T-cell-mediated immune responses effectively and accurately.
PE/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P22646
Gene ID:
12501
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.