The Mouse CD24 Monoclonal Antibody (APC-conjugated, M1/69) AGEL1893 is a versatile tool for researchers focusing on CD24, a cell surface marker with important roles in immune response and cancer progression. This antibody, derived from mouse hybridoma cells, exhibits strong reactivity with murine samples and is optimized for flow cytometry applications. By specifically binding to the CD24 antigen, it enables precise identification and characterization of CD24-expressing cells in various tissues, offering valuable insights into immune cell populations and potential therapeutic targets.CD24, also known as heat stable antigen, is a glycosylphosphatidylinositol-anchored protein found on the surface of multiple cell types, including immune cells and cancer stem cells. Its involvement in cell adhesion, migration, and signaling pathways highlights its importance in both normal immune function and pathological processes such as tumor development and metastasis.
Research on CD24 has implications for understanding immune cell interactions, identifying cancer biomarkers, and exploring novel treatment strategies in oncology.Utilizing the Mouse CD24 Monoclonal Antibody (APC-conjugated, M1/69) AGEL1893 in experimental studies can provide valuable data on the role of CD24 in immune regulation and cancer biology. Its specificity and reliability make it an essential tool for investigating the complex interplay between CD24 expression and disease progression, contributing to advancements in immunology, oncology, and targeted therapy development.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24807
Gene ID:
12484
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD24 is a 35-45 kD protein also known as Heat Stable Antigen (HSA), Ly-52, or Nectadrin. It is a GPI-linked sialoglycoprotein expressed on lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, and dendritic cells. CD24 expression varies during T and B cell differentiation and is a useful marker for delineating various lymphocyte developmental stages. CD24 serves as an adhesion or costimulatory molecule involved in T and B lymphocyte activation and differentiation by homophilic binding or binding to CD62P.