The Mouse CD24 Monoclonal Antibody (AF488 conjugated, M1/69) is a vital tool for researchers studying CD24, a cell surface protein involved in various cellular processes. This antibody, derived from mouse hybridoma cells, is conjugated with AF488 for fluorescent detection and visualization. It specifically recognizes the CD24 antigen, allowing for precise identification and analysis in a range of experimental settings.CD24 is known for its role in cell adhesion, migration, and signaling pathways, making it a key target in developmental biology, immunology, and cancer research. The monoclonal antibody's high specificity and sensitivity make it an ideal choice for applications such as flow cytometry, immunofluorescence, and immunohistochemistry, providing researchers with valuable insights into CD24 expression and function in different cell populations.
Furthermore, CD24 has been implicated in cancer progression and metastasis, as well as immune regulation and stem cell differentiation. By utilizing the Mouse CD24 Monoclonal Antibody (AF488 conjugated, M1/69), researchers can delve deeper into understanding the intricate roles of CD24 in various biological processes and potentially uncover new therapeutic targets for cancer and other diseases.
Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P24807
Gene ID:
12484
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD24 is a 35-45 kD protein also known as Heat Stable Antigen (HSA), Ly-52, or Nectadrin. It is a GPI-linked sialoglycoprotein expressed on lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, and dendritic cells. CD24 expression varies during T and B cell differentiation and is a useful marker for delineating various lymphocyte developmental stages. CD24 serves as an adhesion or costimulatory molecule involved in T and B lymphocyte activation and differentiation by homophilic binding or binding to CD62P.