APC Anti-Mouse CD206 Antibody [C068C2] (AGEL1656)

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SKU:
AGEL1656
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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APC Anti-Mouse CD206 Antibody [C068C2]

The Mouse CD206 Monoclonal Antibody (APC conjugated) is a specialized research tool offered by Assay Genie to facilitate the study of CD206, also known as macrophage mannose receptor. This antibody, meticulously developed for precise recognition of CD206, is a key tool for investigating the functions of this important cell surface molecule in various biological contexts. By binding specifically to CD206, researchers can analyze its expression and activity in different cell types, providing valuable insights into its role in immunology, inflammation, and cancer research.CD206 is a vital receptor involved in the recognition and clearance of glycoproteins, making it a crucial player in the immune response and antigen presentation processes. Its functions in modulating macrophage activity and antigen uptake have significant implications for understanding both innate and adaptive immune responses.

By utilizing the Mouse CD206 Monoclonal Antibody (APC conjugated), researchers can delve deeper into the mechanisms underlying immune regulation, cancer progression, and infectious disease pathogenesis where CD206 is known to play a significant role.This antibody, meticulously validated for its specificity and sensitivity, offers researchers the confidence to explore CD206-related research questions with precision and accuracy. Its applicability in flow cytometry and other techniques make it a versatile tool for investigating the intricate roles of CD206 in diverse biological systems. Dive into the intricate world of CD206 biology with the Mouse CD206 Monoclonal Antibody (APC conjugated) from Assay Genie and unlock new avenues of research in immunology, oncology, and beyond.

Product Title:APC Anti-Mouse CD206 Antibody [C068C2]
SKU:AGEL1656
Size:25µg, 100µg
Clone No:C068C2
Synonyms:MMR;MR;MRC1;macrophage mannose receptor;mannose receptor ;
Host Species:Rat
Reactivity:Mouse
Application:FCM;ICFCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q61830
Gene ID:17533
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.

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