The Mouse CD1d Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) [19G11] (AGEL0814) is a valuable tool for researchers studying immune responses in mouse models. This monoclonal antibody, clone 19G11, specifically targets CD1d, a cell surface molecule involved in presenting lipid antigens to natural killer T (NKT) cells. The PERCP-Cyanine5.5 conjugation allows for easy detection and analysis of CD1d expression using flow cytometry or microscopy techniques.CD1d is essential for the activation and regulation of NKT cells, which play a crucial role in various immune responses, including antitumor immunity and autoimmune diseases.
Therefore, studying CD1d expression and function using this antibody can provide insights into immune system modulation and potential therapeutic interventions.Whether investigating the role of NKT cells in cancer immunotherapy or exploring the mechanisms of autoimmune diseases, the Mouse CD1d Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) [19G11] (AGEL0814) is a reliable tool for immunology research in mouse models.
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P11609
Gene ID:
12479
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR.