PE/Cyanine5.5 Anti-Mouse CD1d Antibody [19G11] (AGEL0813)

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SKU:
AGEL0813
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD1d Antibody [19G11]

The Mouse CD1d Monoclonal Antibody (PE/Cyanine5.5 Conjugated, 19G11, AGEL0813) is a cutting-edge tool for researchers investigating CD1d, a key protein involved in immune responses, particularly in the realm of antigen presentation to natural killer T (NKT) cells. This monoclonal antibody, conjugated with PE/Cyanine5.5, offers high sensitivity and specificity in detecting CD1d protein in mouse samples. Its versatility extends to applications such as flow cytometry and immunofluorescence, enabling precise visualization and analysis of CD1d expression in various cellular contexts.CD1d, a non-classical major histocompatibility complex (MHC) class I-like protein, plays a crucial role in presenting lipid antigens to NKT cells, facilitating their activation and promoting immune responses against pathogens and tumors.

The 19G11 monoclonal antibody specifically targets CD1d, providing researchers with a tool to explore the intricate mechanisms of antigen presentation and NKT cell activation. This antibody is instrumental in studies aimed at understanding the role of CD1d in immunity, autoimmune diseases, infectious diseases, and cancer immunotherapy.By utilizing the Mouse CD1d Monoclonal Antibody (PE/Cyanine5.5 Conjugated, 19G11, AGEL0813), researchers gain a powerful resource to unravel the complexities of CD1d-mediated immune responses and potentially pave the way for innovative therapeutic strategies targeting NKT cell activation pathways.

Product Title:PE/Cyanine5.5 Anti-Mouse CD1d Antibody [19G11]
SKU:AGEL0813
Size:50 Tests, 100 Tests, 200 Tests
Clone No:19G11
Synonyms:Antigen-presenting glycoprotein CD1d1;Cd1d1;CD1d.1;Cd1d1;Cd1.1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11609
Gene ID:12479
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR.

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