APC Anti-Mouse CD1d Antibody [19G11] (AGEL0809)

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SKU:
AGEL0809
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
19G11
Conjugation:
APC
Frequently bought together:

Description

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APC Anti-Mouse CD1d Antibody [19G11]

The Mouse CD1d Monoclonal Antibody (APC Conjugated) 19G11 (AGEL0809) is a vital tool for research in immunology, particularly focusing on CD1d, a glycoprotein involved in antigen presentation to natural killer T (NKT) cells. This antibody, derived from a mouse hybridoma, exhibits high specificity for mouse CD1d and is conjugated to allophycocyanin (APC) for efficient detection in flow cytometry and fluorescence-based assays.CD1d is a key player in the activation and regulation of NKT cells, which bridge the innate and adaptive immune responses. By binding specifically to mouse CD1d, the 19G11 antibody enables precise identification and characterization of CD1d-expressing cells in various experimental systems.

This makes it an invaluable tool for investigating the role of NKT cells in immune surveillance, tolerance, and response to pathogens.The versatile nature of the Mouse CD1d Monoclonal Antibody (APC Conjugated) 19G11 (AGEL0809) makes it well-suited for a wide range of research applications, including immunophenotyping, cell sorting, and functional studies involving NKT cells in immune-related diseases such as autoimmunity, infectious diseases, and cancer. Researchers looking to explore the intricate interactions between NKT cells and CD1d can benefit greatly from the specificity and reliability of this monoclonal antibody.

Product Title:APC Anti-Mouse CD1d Antibody [19G11]
SKU:AGEL0809
Size:50 Tests, 100 Tests, 200 Tests
Clone No:19G11
Synonyms:Antigen-presenting glycoprotein CD1d1;Cd1d1;CD1d.1;Cd1d1;Cd1.1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11609
Gene ID:12479
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR.

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