The Mouse CD1d Monoclonal Antibody (19G11, AGEL0147) offered by Assay Genie is a vital tool for researchers studying immune responses and immunology in mice. This monoclonal antibody specifically targets CD1d, a crucial cell surface molecule involved in antigen presentation to natural killer T cells. Developed for use in various applications, including flow cytometry, immunoprecipitation, and immunohistochemistry, the mouse CD1d monoclonal antibody provides high specificity and sensitivity in detecting CD1d expression in mouse samples. This antibody has been rigorously validated to ensure reliable and reproducible results in experimental settings.
The CD1d molecule is known for its role in lipid antigen presentation and activation of natural killer T cells, making it a key player in the regulation of immune responses. Research using the Mouse CD1d Monoclonal Antibody (19G11, AGEL0147) can shed light on the functions of CD1d in immunity, autoimmune diseases, and infectious diseases, offering valuable insights for therapeutic development and immune modulation strategies.Ensure the success of your immunological research with the Mouse CD1d Monoclonal Antibody (19G11, AGEL0147) from Assay Genie, a reliable reagent for precise and accurate detection of CD1d in mouse models.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR.