Purified Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL0428)

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SKU:
AGEL0428
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
CXCR3-173
Conjugation:
Unconjugated
Applications:
FC
Frequently bought together:

Description

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Purified Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 Monoclonal Antibody (CXCR3-173) from AssayGenie (AGEL0428) is a cutting-edge tool designed for researchers studying the CXCR3 protein, a key regulator of immune and inflammatory responses. This monoclonal antibody is specifically optimized for detecting and analyzing CXCR3 in mouse samples, offering high sensitivity and specificity for a variety of experimental applications.CXCR3, a chemokine receptor, is known for its role in directing the migration and activation of immune cells in response to inflammation and infection. By targeting CXCR3 with this monoclonal antibody, researchers can gain insights into the intricate mechanisms of immune cell recruitment and function in different disease contexts.

Validated for use in techniques such as immunofluorescence, flow cytometry, and immunohistochemistry, the Mouse CD183 Monoclonal Antibody (CXCR3-173) provides researchers with a reliable tool to explore the dynamic interactions of CXCR3 with its ligands and downstream signaling pathways. This antibody's versatility and specificity make it an invaluable asset for investigations in immunology, oncology, and infectious diseases.Uncover the role of CXCR3 in immune responses and inflammation with the Mouse CD183 Monoclonal Antibody (CXCR3-173) from AssayGenie. Trust in its performance and precision to enhance your research endeavors and advance our understanding of immune system regulation.

Product Title:Purified Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL0428
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Purified Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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