FITC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1428)

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SKU:
AGEL1428
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody FITC Conjugated (CXCR3-173) is a valuable tool for research involving the CXCR3 chemokine receptor, a key player in immune cell trafficking and inflammation. This monoclonal antibody, specifically designed for use in flow cytometry applications, is highly specific to mouse samples and has been validated for its performance and reliability.The CXCR3 receptor is known for its involvement in directing immune cells towards sites of inflammation and infection. By targeting CXCR3 with this antibody, researchers can accurately detect and quantify CXCR3 expression on immune cells, helping to unravel the intricate mechanisms of immune responses and inflammatory processes.

Furthermore, the FITC conjugation of this antibody enables fluorescent detection, allowing for precise visualization and analysis of CXCR3-expressing cells. This feature makes it particularly useful for investigating immune responses in various biological contexts, such as infection, autoimmunity, and cancer.In summary, the Mouse CD183 (CXCR3) Monoclonal Antibody FITC Conjugated (CXCR3-173) offers a reliable and specific tool for studying the role of CXCR3 in immune cell function and inflammatory pathways, making it a must-have for researchers in immunology and related fields.

Product Title:FITC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1428
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:FITC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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