GenieFluor 647 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1436)

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SKU:
AGEL1436
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody (AF647 Conjugated) (CXCR3-173) is a cutting-edge tool designed for research applications involving the CXCR3 chemokine receptor. This monoclonal antibody, conjugated with AF647 for enhanced detection capabilities, is highly specific to mouse samples and is validated for use in various experimental techniques, including flow cytometry and immunofluorescence.CXCR3 is a key receptor involved in the recruitment and activation of immune cells, particularly T cells, in response to inflammatory signals. Its role in regulating immune responses and influencing cell migration makes it a crucial target for studies in immunology, inflammation, and autoimmune diseases.

By precisely binding to the CXCR3 receptor, this monoclonal antibody enables researchers to analyze and understand the expression and activity of CXCR3 in different cell populations, facilitating investigations into immune cell function and potential therapeutic interventions.Whether exploring immune cell trafficking in inflammatory conditions, investigating the role of chemokine receptors in cancer metastasis, or studying immune responses in various disease contexts, the Mouse CD183 (CXCR3) Monoclonal Antibody (AF647 Conjugated) (CXCR3-173) offers a reliable and specific tool for advancing research in the field of immunology.

Product Title:GenieFluor 647 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1436
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor 647 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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