GenieFluor 488 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1435)

(No reviews yet) Write a Review
SKU:
AGEL1435
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
CXCR3-173
Conjugation:
AF 488
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 488 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody (AF488 conjugated) (CXCR3-173) is a valuable tool for researchers studying the CXCR3 protein, a chemokine receptor involved in inflammatory responses and immune cell trafficking. This monoclonal antibody, conjugated with AF488 for fluorescence detection, is specifically designed for use in flow cytometry and immunofluorescence applications.CXCR3 is known for its role in modulating immune responses, particularly in the context of inflammation and immune cell migration. By targeting CXCR3 with this monoclonal antibody, researchers can detect and analyze the expression of this protein in various cell types, providing insights into its function in both normal physiology and disease states.

The AF488 conjugation of this antibody allows for sensitive and specific detection of CXCR3 in experimental setups, making it a versatile tool for researchers in immunology, inflammation, and other related fields. By utilizing this antibody, scientists can gain a deeper understanding of the role of CXCR3 in immune regulation and potentially identify novel therapeutic targets for immune-related disorders.

Product Title:GenieFluor 488 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1435
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor 488 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

0 Reviews

View AllClose

Related Products