The Mouse CD16/32 Monoclonal Antibody (PE-Cyanine7 Conjugated, 2.4G2, AGL0592) from AssayGenie is a valuable tool for research involving mouse immune cells and their receptors. This antibody specifically targets CD16/32, which are cell surface molecules known to be involved in immune responses and the regulation of inflammation.With its PE-Cyanine7 conjugation, this antibody enables precise and sensitive detection of CD16/32 in flow cytometry and other immunological assays. Its monoclonal nature ensures high specificity and consistency in binding to the target, making it a reliable choice for studies in immunology, cancer research, and beyond.
CD16/32, also referred to as FcγRIII/FcγRII, plays a crucial role in mediating antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis by immune cells. Understanding the expression and function of CD16/32 is essential for unraveling the complex mechanisms of immune responses and developing targeted therapies for various diseases.By utilizing the Mouse CD16/32 Monoclonal Antibody (PE-Cyanine7 Conjugated, 2.4G2, AGL0592), researchers can delve deeper into the intricacies of mouse immune system regulation and potentially uncover novel insights that pave the way for innovative therapeutic approaches.
Product Title:
PE/Cyanine7 Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:
AGEL0592
Size:
25µg, 100µg
Clone No:
2.4G2
Synonyms:
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
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