The Mouse CD16/32 Monoclonal Antibody PE Conjugated (2.4G2) is a powerful tool for research involving the CD16/32 receptor, key in regulating immune responses and cell activation. This highly specific antibody, produced using stringent processes, is optimized for use in flow cytometry analyses, allowing for precise identification and quantification of CD16/32-expressing cells in various biological samples.CD16/32, also known as Fc gamma receptor III (FcgRIII) and Fc gamma receptor II (FcgRII), plays a significant role in mediating immune responses by binding to the Fc portion of immunoglobulins. Its presence on immune cells like macrophages, monocytes, and dendritic cells makes it a crucial player in antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis processes.
By using this antibody, researchers can explore the functionality and expression patterns of CD16/32 in different immune cell populations, advancing our understanding of immune regulation and response mechanisms.The ability of the Mouse CD16/32 Monoclonal Antibody PE Conjugated (2.4G2) to provide accurate and reliable data on CD16/32 expression levels makes it an invaluable asset for immunologists, cell biologists, and researchers studying immune-related disorders such as autoimmune diseases, infectious pathogens, and cancer. By delving into the intricacies of CD16/32 function, this antibody opens up new avenues for therapeutic interventions and the development of targeted immunotherapies for various health conditions.
Product Title:
PE Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:
AGEL0588
Size:
25µg, 100µg
Clone No:
2.4G2
Synonyms:
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
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