The Mouse CD16/32 Monoclonal Antibody (FITC Conjugated 2.4G2) is a valuable tool for researchers studying immune responses and cell surface molecules in mice. This antibody, offered by Assay Genie, is specifically designed to target CD16/32, which are important markers involved in immune cell function.CD16/32, also known as Fc receptors, play a crucial role in mediating various immune responses such as phagocytosis and antibody-dependent cell-mediated cytotoxicity. By specifically binding to CD16/32, this monoclonal antibody enables researchers to detect and analyze these cell surface molecules in different cell types and tissues, thereby facilitating studies in immunology, inflammation, and infectious diseases.The FITC conjugation of the 2.4G2 antibody provides the added benefit of fluorescent labeling, allowing for visualization and quantification of CD16/32 expression in flow cytometry and immunofluorescence assays.
This feature enhances the precision and accuracy of experimental results, making this antibody an ideal choice for researchers looking to investigate immune responses in mice at the cellular level.By utilizing the Mouse CD16/32 Monoclonal Antibody (FITC Conjugated 2.4G2) from Assay Genie, researchers can delve deeper into the intricate mechanisms of immune regulation and function in mouse models, advancing our understanding of immunological processes and potentially paving the way for the development of novel therapeutic strategies targeting immune-related disorders.
Product Title:
FITC Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:
AGEL0577
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
2.4G2
Synonyms:
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
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