APC Anti-Mouse CD150 Antibody [TC15-12F12.2] (AGEL1882)

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SKU:
AGEL1882
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
TC15-12F12.2
Conjugation:
APC
Frequently bought together:

Description

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APC Anti-Mouse CD150 Antibody [TC15-12F12.2]

The Mouse CD150 Monoclonal Antibody (APC Conjugated, TC15-12F12.2) is a cutting-edge tool designed for researchers studying CD150, a key cell surface marker involved in immune cell activation and regulation. This antibody, meticulously developed and validated by Assay Genie, offers exceptional specificity and sensitivity for detecting CD150 protein in mouse samples specifically conjugated to APC for fluorescence-based assays.CD150, also known as SLAM (Signaling Lymphocytic Activation Molecule), is a crucial immune regulatory molecule that mediates signal transduction in various immune cell types, including T cells, B cells, and dendritic cells. Its versatile role in modulating immune responses and controlling cell activation makes it a central focus in immunological research, particularly in areas related to infectious diseases, immune disorders, and cancer.

By utilizing the Mouse CD150 Monoclonal Antibody (APC Conjugated, TC15-12F12.2), researchers gain a powerful tool to investigate the expression and function of CD150 in diverse cellular contexts. This antibody's high specificity and consistent performance make it a valuable asset for flow cytometry, immunofluorescence, and other techniques aimed at unraveling the intricate mechanisms underlying immune system regulation and pathology.In summary, the Mouse CD150 Monoclonal Antibody (APC Conjugated, TC15-12F12.2) from Assay Genie represents a sophisticated and reliable solution for scientists seeking to explore the multifaceted roles of CD150 in immunology and beyond. This advanced reagent holds tremendous potential for accelerating discoveries and advancing our understanding of immune system dynamics and pathological processes.

Product Title:APC Anti-Mouse CD150 Antibody [TC15-12F12.2]
SKU:AGEL1882
Size:50 Tests, 100 Tests, 200 Tests
Clone No:TC15-12F12.2
Synonyms:Slam;Slamf1;CD 150;Signaling lymphocytic activation molecule;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, λ
Isotype Control:APC Rat IgG2a, λ Isotype Control[B39-4]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9QUM4
Gene ID:27218
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

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